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Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase
Many microorganisms use flavin-dependent thymidylate synthase (FDTS) to synthesize the essential nucleotide 2′-deoxythymidine-5′-monophosphate (dTMP) from 2′-deoxyuridine-5′-monophosphate (dUMP), 5,10-methylenetetrahydrofolate (CH(2)THF), and NADPH. FDTSs have a structure that is unrelated to the th...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5939375/ https://ncbi.nlm.nih.gov/pubmed/27214228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00510 |
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