Dynamic activation and regulation of the mitogen-activated protein kinase p38

Mitogen-activated protein kinases, which include p38, are essential for cell differentiation and autophagy. The current model for p38 activation involves activation-loop phosphorylation with subsequent substrate binding leading to substrate phosphorylation. Despite extensive efforts, the molecular m...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Kumar, Ganesan Senthil, Clarkson, Michael W., Kunze, Micha B. A., Granata, Daniele, Wand, A. Joshua, Lindorff-Larsen, Kresten, Page, Rebecca, Peti, Wolfgang
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939092/
https://ncbi.nlm.nih.gov/pubmed/29666261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721441115
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires