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Detection of DNA Double Strand Breaks by γH2AX Does Not Result in 53bp1 Recruitment in Mouse Retinal Tissues

Gene editing is an attractive potential treatment of inherited retinopathies. However, it often relies on endogenous DNA repair. Retinal DNA repair is incompletely characterized in humans and animal models. We investigated recruitment of the double stranded break (DSB) repair complex of γH2AX and 53...

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Bibliografske podrobnosti
izdano v:Front Neurosci
Main Authors: Müller, Brigitte, Ellinwood, N. M., Lorenz, Birgit, Stieger, Knut
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938408/
https://ncbi.nlm.nih.gov/pubmed/29765300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00286
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