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Detection of DNA Double Strand Breaks by γH2AX Does Not Result in 53bp1 Recruitment in Mouse Retinal Tissues

Gene editing is an attractive potential treatment of inherited retinopathies. However, it often relies on endogenous DNA repair. Retinal DNA repair is incompletely characterized in humans and animal models. We investigated recruitment of the double stranded break (DSB) repair complex of γH2AX and 53...

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書目詳細資料
發表在:Front Neurosci
Main Authors: Müller, Brigitte, Ellinwood, N. M., Lorenz, Birgit, Stieger, Knut
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938408/
https://ncbi.nlm.nih.gov/pubmed/29765300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00286
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