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Discovery of Natural Products as Novel and Potent FXR Antagonists by Virtual Screening
Farnesoid X receptor (FXR) is a member of nuclear receptor family involved in multiple physiological processes through regulating specific target genes. The critical role of FXR as a transcriptional regulator makes it a promising target for diverse diseases, especially those related to metabolic dis...
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| Publicado en: | Front Chem |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5936786/ https://ncbi.nlm.nih.gov/pubmed/29761098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00140 |
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