Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis

AIM: To explore the potent inhibitor from one of the Traditional Chinese medicine (TCM), Epimedium sagittatum. METHODS: We predicted the potent compound, ES03b, de novo evolution from the four Epimedium sagittatum components were verified by molecular docking, pharmacophore analysis, and analysis of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, Chien-yu, Chang, Yea-huey, Bau, Da-tian, Huang, Hung-jin, Tsai, Fuu-jen, Tsai, Chang-hai, Chen, Calvin Yu-chian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006686/
https://ncbi.nlm.nih.gov/pubmed/19597523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.100
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados