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Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis
AIM: To explore the potent inhibitor from one of the Traditional Chinese medicine (TCM), Epimedium sagittatum. METHODS: We predicted the potent compound, ES03b, de novo evolution from the four Epimedium sagittatum components were verified by molecular docking, pharmacophore analysis, and analysis of...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4006686/ https://ncbi.nlm.nih.gov/pubmed/19597523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.100 |
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