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IFN-α augments natural killer-mediated antibody-dependent cellular cytotoxicity of HIV-1-infected autologous CD4(+) T cells regardless of major histocompatibility complex class 1 downregulation

DESIGN: We have previously shown that IFN-α stimulation augments direct natural killer (NK) cell lysis of autologous CD4(+) primary T cells infected with certain HIV-1 isolates based upon major histocompatibility complex class 1 (MHC-1) downregulation capacity. Here, we investigated if antibody-depe...

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Bibliografiska uppgifter
I publikationen:AIDS
Huvudupphovsmän: Tomescu, Costin, Tebas, Pablo, Montaner, Luis J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934752/
https://ncbi.nlm.nih.gov/pubmed/28225449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001380
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