HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

Major-histocompatibility-complex (MHC) proteins are used to display, on the surface of a cell, peptides derived from foreign material — such as a virus — that is infecting that cell. Cytotoxic T lymphocytes then recognize and kill the infected cell. The HIV-1 Nef protein downregulates the cell-surfa...

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Hlavní autoři: Piguet, Vincent, Wan, Lei, Borel, Christelle, Mangasarian, Aram, Demaurex, Nicolas, Thomas, Gary, Trono, Didier
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475706/
https://ncbi.nlm.nih.gov/pubmed/10707087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/35004038
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