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HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes
Major-histocompatibility-complex (MHC) proteins are used to display, on the surface of a cell, peptides derived from foreign material — such as a virus — that is infecting that cell. Cytotoxic T lymphocytes then recognize and kill the infected cell. The HIV-1 Nef protein downregulates the cell-surfa...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1475706/ https://ncbi.nlm.nih.gov/pubmed/10707087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/35004038 |
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