Antisecretory Factor-mediated Inhibition of Cell Volume Dynamics Produces Anti-tumor Activity in Glioblastoma

Interstitial fluid pressure (IFP) presents a barrier to drug uptake in solid tumors, including the aggressive primary brain tumor glioblastoma multiforme (GBM). It remains unclear how fluid dynamics impacts tumor progression and can be targeted therapeutically. To address this issue, a novel telemet...

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Publicado en:Mol Cancer Res
Autores principales: Ilkhanizadeh, Shirin, Sabelström, Hanna, Miroshnikova, Yekaterina A., Frantz, Aaron, Zhu, Wen, Idilli, Aurora, Lakins, Jon N., Schmidt, Christin, Quigley, David A., Fenster, Trenten, Yuan, Edith, Trzeciak, Jacqueline R., Saxena, Supna, Lindberg, Olle R., Mouw, Janna K., Burdick, Jason A., Magnitsky, Sergey, Berger, Mitchel S., Phillips, Joanna J., Arosio, Daniele, Sun, Dandan, Weaver, Valerie M., Weiss, William A., Persson, Anders I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932284/
https://ncbi.nlm.nih.gov/pubmed/29431617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0413
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