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NT-11 TARGETING INTERSTITIAL FLUID PRESSURE TO REDUCE TUMOR GROWTH AND INCREASE DRUG UPTAKE IN BRAIN TUMORS
High interstitial fluid pressure (IFP) represents a barrier for drug uptake in human GBM, the most common malignant primary brain tumor in adults. Increased IFP is due to leakiness of blood vessels and reduced drainage of fluid. This accumulation of fluid and high cell density compresses tumor tissu...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218420/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou265.11 |
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