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Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

Forward genetic screens using reporter genes inserted into the heterochromatin have been extensively used to investigate mechanisms of epigenetic control in model organisms. Technologies including short hairpin RNAs (shRNAs) and clustered regularly interspaced short palindromic repeats (CRISPR) have...

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Detaylı Bibliyografya
Yayımlandı:J Vis Exp
Asıl Yazarlar: Leko, Vid, Sripathy, Smitha, Adrianse, Robin L., Loe, Taylor, Park, Angela, Lao, Uyen, Foss, Eric J., Bartolomei, Marisa S., Bedalov, Antonio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MyJove Corporation 2018
Konular:
Genetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931421/
https://ncbi.nlm.nih.gov/pubmed/29553562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56398
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