Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

Forward genetic screens using reporter genes inserted into the heterochromatin have been extensively used to investigate mechanisms of epigenetic control in model organisms. Technologies including short hairpin RNAs (shRNAs) and clustered regularly interspaced short palindromic repeats (CRISPR) have...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Vis Exp
मुख्य लेखकों: Leko, Vid, Sripathy, Smitha, Adrianse, Robin L., Loe, Taylor, Park, Angela, Lao, Uyen, Foss, Eric J., Bartolomei, Marisa S., Bedalov, Antonio
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MyJove Corporation 2018
विषय:
Genetics
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931421/
https://ncbi.nlm.nih.gov/pubmed/29553562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56398
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