Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors

Recently, FGFR1 was found to be overexpressed in osteosarcoma and represents an important target for precision medicine. However, because targeted cancer therapy based on FGFR inhibitors has so far been less efficient than expected, a detailed understanding of the target is important. We have here a...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Kostas, Michal, Haugsten, Ellen Margrethe, Zhen, Yan, Sørensen, Vigdis, Szybowska, Patrycja, Fiorito, Elisa, Lorenz, Susanne, Jones, Nina, de Souza, Gustavo Antonio, Wiedlocha, Antoni, Wesche, Jørgen
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930401/
https://ncbi.nlm.nih.gov/pubmed/29371290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000538
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