Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors

Recently, FGFR1 was found to be overexpressed in osteosarcoma and represents an important target for precision medicine. However, because targeted cancer therapy based on FGFR inhibitors has so far been less efficient than expected, a detailed understanding of the target is important. We have here a...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Proteomics
Asıl Yazarlar: Kostas, Michal, Haugsten, Ellen Margrethe, Zhen, Yan, Sørensen, Vigdis, Szybowska, Patrycja, Fiorito, Elisa, Lorenz, Susanne, Jones, Nina, de Souza, Gustavo Antonio, Wiedlocha, Antoni, Wesche, Jørgen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2018
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930401/
https://ncbi.nlm.nih.gov/pubmed/29371290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000538
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