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Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II

Lung-specific overexpression of prostacyclin synthase (PGIS) decreases tumor initiation in murine lung cancer models. Prostacyclin analogs prevent lung tumor formation in mice and reverse bronchial dysplasia in former smokers. However, the effect of prostacyclin on lung cancer progression has not be...

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Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Li, Howard Y., McSharry, Maria, Walker, Deandra, Johnson, Amber, Kwak, Jeff, Bullock, Bonnie, Neuwelt, Alexander, Poczobutt, Joanna M., Sippel, Trisha R., Keith, Robert L., Weiser-Evans, Mary C. M., Clambey, Eric, Nemenoff, Raphael A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927539/
https://ncbi.nlm.nih.gov/pubmed/29721380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1423182
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