Complement activation via a C3a receptor pathway alters CD4+ T lymphocytes and mediates lung cancer progression

The complement cascade is a part of the innate immune system which acts primarily to remove pathogens and injured cells. However, complement activation is also peculiarly associated with tumor progression. Here we report mechanistic insights into this association in multiple immunocompetent orthotop...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Kwak, Jeff W., Laskowski, Jennifer, Li, Howard Y., McSharry, Maria V., Sippel, Trisha R., Bullock, Bonnie L., Johnson, Amber M., Poczobutt, Joanna M., Neuwelt, Alexander J., Malkoski, Stephen P., Weiser-Evans, Mary C., Lambris, John, Clambey, Eric T., Thurman, Joshua M., Nemenoff, Raphael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810934/
https://ncbi.nlm.nih.gov/pubmed/29118090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0240
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