The Tumor Microenvironment Regulates Sensitivity of Murine Lung Tumors to PD-1/PD-L1 Antibody Blockade

Immune checkpoint inhibitors targeting the interaction between programmed cell death-1 (PD-1) and its ligand PD-L1 induce tumor regression in a subset of non-small cell lung cancer patients. However, clinical response rates are less than 25%. Evaluation of combinations of immunotherapy with existing...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Li, Howard Y., McSharry, Maria, Bullock, Bonnie, Nguyen, Teresa T., Kwak, Jeff, Poczobutt, Joanna M., Sippel, Trisha R., Heasley, Lynn E., Weiser-Evans, Mary C., Clambey, Eric T., Nemenoff, Raphael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787226/
https://ncbi.nlm.nih.gov/pubmed/28819064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0365
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