Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti–PD-1 response in NSCLC

Targeting PD-1/PD-L1 is only effective in ∼20% of lung cancer patients, but determinants of this response are poorly defined. We previously observed differential responses of two murine K-Ras–mutant lung cancer cell lines to anti–PD-1 therapy: CMT167 tumors were eliminated, whereas Lewis Lung Carcin...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Bullock, Bonnie L, Kimball, Abigail K, Poczobutt, Joanna M, Neuwelt, Alexander J, Li, Howard Y, Johnson, Amber M, Kwak, Jeff W, Kleczko, Emily K, Kaspar, Rachael E, Wagner, Emily K, Hopp, Katharina, Schenk, Erin L, Weiser-Evans, Mary CM, Clambey, Eric T, Nemenoff, Raphael A
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537751/
https://ncbi.nlm.nih.gov/pubmed/31133614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900328
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