Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti–PD-1 response in NSCLC

Targeting PD-1/PD-L1 is only effective in ∼20% of lung cancer patients, but determinants of this response are poorly defined. We previously observed differential responses of two murine K-Ras–mutant lung cancer cell lines to anti–PD-1 therapy: CMT167 tumors were eliminated, whereas Lewis Lung Carcin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Life Sci Alliance
Päätekijät: Bullock, Bonnie L, Kimball, Abigail K, Poczobutt, Joanna M, Neuwelt, Alexander J, Li, Howard Y, Johnson, Amber M, Kwak, Jeff W, Kleczko, Emily K, Kaspar, Rachael E, Wagner, Emily K, Hopp, Katharina, Schenk, Erin L, Weiser-Evans, Mary CM, Clambey, Eric T, Nemenoff, Raphael A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Life Science Alliance LLC 2019
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537751/
https://ncbi.nlm.nih.gov/pubmed/31133614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900328
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