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Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti–PD-1 response in NSCLC

Targeting PD-1/PD-L1 is only effective in ∼20% of lung cancer patients, but determinants of this response are poorly defined. We previously observed differential responses of two murine K-Ras–mutant lung cancer cell lines to anti–PD-1 therapy: CMT167 tumors were eliminated, whereas Lewis Lung Carcin...

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Dades bibliogràfiques
Publicat a:Life Sci Alliance
Autors principals: Bullock, Bonnie L, Kimball, Abigail K, Poczobutt, Joanna M, Neuwelt, Alexander J, Li, Howard Y, Johnson, Amber M, Kwak, Jeff W, Kleczko, Emily K, Kaspar, Rachael E, Wagner, Emily K, Hopp, Katharina, Schenk, Erin L, Weiser-Evans, Mary CM, Clambey, Eric T, Nemenoff, Raphael A
Format: Artigo
Idioma:Inglês
Publicat: Life Science Alliance LLC 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537751/
https://ncbi.nlm.nih.gov/pubmed/31133614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900328
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