Cisplatin‐incorporated Polymeric Micelles Eliminate Nephrotoxicity, While Maintaining Antitumor Activity

cis‐Diamminedichloroplatinum (II) (cisplatin, CDDP), a potent anticancer agent, was bound to the aspartic acid residues of poly(ethylene glycol)‐poly(aspartic acid) (PEG‐P(ASP)) block copolymer by ligand substitution reaction at the platinum atom of CDDP. The polymeric drug thus obtained was observe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Jpn J Cancer Res
Hauptverfasser: Mizumura, Yasuo, Matsumura, Yasuhiro, Hamaguchi, Tetsuya, Nishiyama, Nobuhiro, Kataoka, Kazunori, Kawaguchi, Takanori, Hrushesky, William J. M., Moriyasu, Fuminori, Kakizoe, Tadao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2001
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926709/
https://ncbi.nlm.nih.gov/pubmed/11267944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2001.tb01099.x
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge