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Incorporation of the Anticancer Agent KRN5500 into Polymeric Micelles Diminishes the Pulmonary Toxicity

KRN5500 is a highly active new semi‐synthetic water‐insoluble anticancer agent. The only mechanism of anticancer activity of KRN5500 described so far is an inhibitory effect on protein synthesis. At the tune of writing, a phase I clinical trial is under way at the National Cancer Center Hospital, To...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Mizumura, Yasuo, Matsumura, Yasuhiro, Yokoyama, Masayuki, Okano, Teruo, Kawaguchi, Takanori, Moriyasu, Fuminori, Kakizoe, Tadao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926897/
https://ncbi.nlm.nih.gov/pubmed/12460465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01229.x
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