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The Novel Anticancer Drug KRN5500 Interacts with, but is Hardly Transported by, Human P‐Glycoprotein
The interaction of the novel anticancer drug KRN5500, a spicamycin derivative, with human Pglycoprotein (P‐gp) was analyzed from the viewpoint of cellular pharmacokinetics, i.e. by means of [(3)H]azidopine photoaffinity labeling, cellular accumulation and transcellular transport experiments. In this...
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| Izdano u: | Jpn J Cancer Res |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Publishing Ltd
2000
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5926333/ https://ncbi.nlm.nih.gov/pubmed/10761713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2000.tb00938.x |
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