Reduction of the Side Effects of an Antitumor Agent, KRN5500, by Incorporation of the Drug into Polymeric Micelles

For intravenous (i.v.) injection of a water‐insoluble antitumor drug, KRN5500, we have successfully incorporated KRN5500 into polymeric micelles. In the present study, in vitro and in vivo antitumor activity against several human tumor cell lines and toxicity in mice of polymeric micelles incorporat...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Matsumura, Yasuhiro, Yokoyama, Masayuki, Kataoka, Kazunori, Okano, Teruo, Sakurai, Yasuhisa, Kawaguchi, Takanori, Kakizoe, Tadao
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 1999
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925985/
https://ncbi.nlm.nih.gov/pubmed/10076575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00675.x
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