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Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats

In spite of the clinical usefulness of cisplatin (CDDP), there are many occasions in which it is difficult to continue the administration of CDDP due to its nephrotoxicity and neurotoxicity. We examined the incorporation of CDDP into polymeric micelles to see if this allowed the resolution of these...

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Bibliografiske detaljer
Main Authors: Uchino, H, Matsumura, Y, Negishi, T, Koizumi, F, Hayashi, T, Honda, T, Nishiyama, N, Kataoka, K, Naito, S, Kakizoe, T
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361620/
https://ncbi.nlm.nih.gov/pubmed/16222314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602772
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