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Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats

In spite of the clinical usefulness of cisplatin (CDDP), there are many occasions in which it is difficult to continue the administration of CDDP due to its nephrotoxicity and neurotoxicity. We examined the incorporation of CDDP into polymeric micelles to see if this allowed the resolution of these...

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Main Authors: Uchino, H, Matsumura, Y, Negishi, T, Koizumi, F, Hayashi, T, Honda, T, Nishiyama, N, Kataoka, K, Naito, S, Kakizoe, T
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361620/
https://ncbi.nlm.nih.gov/pubmed/16222314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602772
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