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Efficient Production of Adeno‐associated Virus Vectors Using Split‐type Helper Plasmids

Adeno‐associated virus (AAV) vectors are potentially useful vehicles for the delivery of therapeutic genes into human cells. To determine the optimal expression pattern of AAV proteins (Rep78, Rep68, Rep52, Rep40, and Cap proteins) for packaging the recombinant AAV genome, helper plasmids were split...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Ogasawara, Yoji, Urabe, Masashi, Kogure, Katsuhiro, Kume, Akihiro, Colosi, Peter, Kurtzman, Gary J., Ozawa, Keiya
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926094/
https://ncbi.nlm.nih.gov/pubmed/10363588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00772.x
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