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Fas and Mutant Estrogen Receptor Chimeric Gene: A Novel Suicide Vector for Tamoxifen‐inducible Apoptosis

Several cancer gene therapy strategies involve suicide genes to kill the neoplasm, or to regulate effector cells such as lymphocytes. We have developed an inducible apoptosis system with a Fasestrogen receptor fusion protein (MfasER) for rapid elimination of transduced cells. In the present study, w...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kodaira, Hiroshi, Kume, Akihiro, Ogasawara, Yoji, Urabe, Masashi, Kitano, Kiyoshi, Kakizuka, Akira, Ozawa, Keiya
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921882/
https://ncbi.nlm.nih.gov/pubmed/9738981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb03279.x
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