Charged-to-Alanine Scanning Mutagenesis of the N-Terminal Half of Adeno-Associated Virus Type 2 Rep78 Protein

The adeno-associated virus (AAV) Rep78 and Rep68 proteins are required for site-specific integration of the AAV genome into the AAVS1 locus (19q13.3-qter) as well as for viral DNA replication. Rep78 and Rep68 bind to the GAGC motif on the inverted terminal repeat (ITR) and cut at the trs (terminal r...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Urabe, Masashi, Hasumi, Yoko, Kume, Akihiro, Surosky, Richard T., Kurtzman, Gary J., Tobita, Kiyotake, Ozawa, Keiya
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 1999
विषय:
Replication
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC104024/
https://ncbi.nlm.nih.gov/pubmed/10074114
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