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Adeno‐associated Virus Vector Containing the Herpes Simplex Virus Thymidine Kinase Gene Causes Complete Regression of Intracerebrally Implanted Human Gliomas in Mice, in Conjunction with Ganciclovir Administration

Adeno‐associated virus (AAV) has attracted considerable interest as a potential vector for gene therapy because of its wide host range, high transduction efficiency, and lack of cytopathogenicity. In this experiment, we evaluated the efficacy of AAV vector containing the herpes simplex virus thymidi...

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Publicat a:Jpn J Cancer Res
Autors principals: Mizuno, Masaaki, Yoshida, Jun, Colosi, Peter, Kurtzman, Gary
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921591/
https://ncbi.nlm.nih.gov/pubmed/9510479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00482.x
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