Combination effect of oncolytic adenovirus therapy and herpes simplex virus thymidine kinase/ganciclovir in hepatic carcinoma animal models

AIM: Oncolytic adenovirus, also called conditionally replicating adenovirus (CRAD), can selectively propagate in tumor cells and cause cell lysis. The released viral progeny can infect neighboring cancer cells, initiating a cascade that can lead to the ultimate destruction of the tumor. Suicide gene...

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Detalhes bibliográficos
Main Authors: Zheng, Fei-qun, Xu, Yin, Yang, Ren-jie, Wu, Bin, Tan, Xiao-hua, Qin, Yi-de, Zhang, Qun-wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002820/
https://ncbi.nlm.nih.gov/pubmed/19363518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.33
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