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Engineering and Characterization of Oncolytic Vaccinia Virus Expressing Truncated Herpes Simplex Virus Thymidine Kinase

Oncolytic viruses are a promising class of anti-tumor agents; however, concerns regarding uncontrolled viral replication have led to the development of a replication-controllable oncolytic vaccinia virus (OVV). The engineering involves replacing the native thymidine kinase (VV-tk) gene, in a Wyeth s...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Islam, S. M. Bakhtiar Ul, Lee, Bora, Jiang, Fen, Kim, Eung-Kyun, Ahn, Soon Cheol, Hwang, Tae-Ho
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016767/
https://ncbi.nlm.nih.gov/pubmed/31963415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010228
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