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Engineering and Characterization of Oncolytic Vaccinia Virus Expressing Truncated Herpes Simplex Virus Thymidine Kinase

Oncolytic viruses are a promising class of anti-tumor agents; however, concerns regarding uncontrolled viral replication have led to the development of a replication-controllable oncolytic vaccinia virus (OVV). The engineering involves replacing the native thymidine kinase (VV-tk) gene, in a Wyeth s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Islam, S. M. Bakhtiar Ul, Lee, Bora, Jiang, Fen, Kim, Eung-Kyun, Ahn, Soon Cheol, Hwang, Tae-Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016767/
https://ncbi.nlm.nih.gov/pubmed/31963415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010228
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