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Characterization of Oncolytic Vaccinia Virus Harboring the Human IFNB1 and CES2 Transgenes

PURPOSE: The purpose of this study was to assess characteristics of SJ-815, a novel oncolytic vaccinia virus lacking a functional thymidine kinase-encoding TK gene, and instead, having two human transgenes: the IFNB1 that encodes interferon β1, and the CES2 that encodes carboxylesterase 2, which met...

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Dettagli Bibliografici
Pubblicato in:Cancer Res Treat
Autori principali: Cho, Euna, Islam, S M Bakhtiar Ul, Jiang, Fen, Park, Ju-Eun, Lee, Bora, Kim, Nam Deuk, Hwang, Tae-Ho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Cancer Association 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962490/
https://ncbi.nlm.nih.gov/pubmed/31401821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2019.161
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