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Proteolysis Targeting Chimeras (PROTACs) of Anaplastic Lymphoma Kinase (ALK)

Anaplastic lymphoma kinase (ALK) activation has been associated with many types of human cancer. Significant efforts have been devoted to development of ALK inhibitors to antagonize the kinase activity of ALK. Four ALK inhibitors have been approved by the FDA to date for treating patients with ALK-p...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Eur J Med Chem
Κύριοι συγγραφείς: Zhang, Chengwei, Han, Xiao-Ran, Yang, Xiaobao, Jiang, Biao, Liu, Jing, Xiong, Yue, Jin, Jian
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924614/
https://ncbi.nlm.nih.gov/pubmed/29627725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.03.071
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