Down Syndrome Critical Region 1 Gene, Rcan1, Helps Maintain a More Fused Mitochondrial Network

RATIONALE: The Regulator of Calcineurin 1 (RCAN1) inhibits calcineurin (CN), a Ca(2+)-activated protein phosphatase important in cardiac remodeling. In humans, RCAN1 is located on chromosome 21 in proximity to the “Down syndrome critical region.” The hearts and brains of Rcan1 KO mice are more susce...

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Bibliografski detalji
Izdano u:Circ Res
Glavni autori: Parra, Valentina, Altamirano, Francisco, Hernández-Fuentes, Carolina P., Tong, Dan, Kyrychenko, Victoriia, Rotter, David, Pedrozo, Zully, Hill, Joseph A., Eisner, Verónica, Lavandero, Sergio, Schneider, Jay W., Rothermel, Beverly A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924463/
https://ncbi.nlm.nih.gov/pubmed/29362227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.311522
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