Regulator of calcineurin 1 (Rcan1) controls growth plasticity of adult pancreas

BACKGROUND & AIMS: Growth of exocrine pancreas is regulated by GI hormones, notably cholecystokinin (CCK). CCK-driven pancreatic growth requires calcineurin (CN), which activates NFATs (Nuclear Factor of Activated T-cells), but the genetic underpinnings and feedback mechanisms that regulate this...

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Autors principals: Gurda, Grzegorz T., Crozier, Stephen J., Ji, Baoan, Ernst, Stephen A., Logsdon, Craig D., Rothermel, Beverly A., Williams, John A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929702/
https://ncbi.nlm.nih.gov/pubmed/20438729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.04.050
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