The Down Syndrome Critical Region Protein RCAN1 Regulates Long-Term Potentiation and Memory via Inhibition of Phosphatase Signaling

Regulator of calcineurin 1 (RCAN1/MCIP1/DSCR1) regulates the calmodulin-dependent phosphatase calcineurin. Because it is located on human chromosome 21, RCAN1 has been postulated to contribute to mental retardation in Down syndrome and has been reported to be associated with neuronal degeneration in...

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Publicat a:J Neurosci
Autors principals: Hoeffer, Charles A., Dey, Asim, Sachan, Nita, Wong, Helen, Patterson, Richard J., Shelton, John M., Richardson, James A., Klann, Eric, Rothermel, Beverly A.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2007
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673398/
https://ncbi.nlm.nih.gov/pubmed/18045910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3974-07.2007
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