The Down Syndrome Critical Region Protein RCAN1 Regulates Long-Term Potentiation and Memory via Inhibition of Phosphatase Signaling

Regulator of calcineurin 1 (RCAN1/MCIP1/DSCR1) regulates the calmodulin-dependent phosphatase calcineurin. Because it is located on human chromosome 21, RCAN1 has been postulated to contribute to mental retardation in Down syndrome and has been reported to be associated with neuronal degeneration in...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Hoeffer, Charles A., Dey, Asim, Sachan, Nita, Wong, Helen, Patterson, Richard J., Shelton, John M., Richardson, James A., Klann, Eric, Rothermel, Beverly A.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673398/
https://ncbi.nlm.nih.gov/pubmed/18045910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3974-07.2007
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