טוען...
D409H GBA1 mutation accelerates the progression of pathology in A53T α-synuclein transgenic mouse model
Heterozygous mutations in glucocerebrosidase 1 (GBA1) are a major genetic risk factor for Parkinson’s disease and Dementia with Lewy bodies. Mutations in GBA1 leads to GBA1 enzyme deficiency, and GBA1-associated parkinsonism has an earlier age of onset and more progressive parkinsonism. To investiga...
שמור ב:
| הוצא לאור ב: | Acta Neuropathol Commun |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5923019/ https://ncbi.nlm.nih.gov/pubmed/29703245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0538-9 |
| תגים: |
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