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Topoisomerase VI senses and exploits both DNA crossings and bends to facilitate strand passage

Type II topoisomerases manage DNA supercoiling and aid chromosome segregation using a complex, ATP-dependent duplex strand passage mechanism. Type IIB topoisomerases and their homologs support both archaeal/plant viability and meiotic recombination. Topo VI, a prototypical type IIB topoisomerase, co...

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Bibliographic Details
Published in:eLife
Main Authors: Wendorff, Timothy J, Berger, James M
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922973/
https://ncbi.nlm.nih.gov/pubmed/29595473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31724
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