Structural similarities between topoisomerases that cleave one or both DNA strands
Type IA and type II DNA topoisomerases are distinguished by their ability to cleave one or two strands, respectively, of a DNA duplex. Both types have been proposed to use an “enzyme-bridging” mechanism, in which a break is formed in a DNA strand and a gap is opened between the broken pieces to allo...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1998
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.7876 |
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