Structural similarities between topoisomerases that cleave one or both DNA strands

Type IA and type II DNA topoisomerases are distinguished by their ability to cleave one or two strands, respectively, of a DNA duplex. Both types have been proposed to use an “enzyme-bridging” mechanism, in which a break is formed in a DNA strand and a gap is opened between the broken pieces to allo...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Berger, James M., Fass, Deborah, Wang, James C., Harrison, Stephen C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9653108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.14.7876
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