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Inhibition of the methyltranferase EZH2 improves aortic performance in experimental thoracic aortic aneurysm
Loss-of-function mutations in genes encoding contractile proteins have been observed in thoracic aortic aneurysms (TAA). To gain insight into the contribution of contractile protein deficiency in the pathogenesis of TAA, we examined human aneurysm samples. We found multiple contractile gene products...
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| 出版年: | JCI Insight |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5922285/ https://ncbi.nlm.nih.gov/pubmed/29515022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97493 |
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