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Inhibition of the methyltranferase EZH2 improves aortic performance in experimental thoracic aortic aneurysm

Loss-of-function mutations in genes encoding contractile proteins have been observed in thoracic aortic aneurysms (TAA). To gain insight into the contribution of contractile protein deficiency in the pathogenesis of TAA, we examined human aneurysm samples. We found multiple contractile gene products...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Lino Cardenas, Christian L., Kessinger, Chase W., MacDonald, Carolyn, Jassar, Arminder S., Isselbacher, Eric M., Jaffer, Farouc A., Lindsay, Mark E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922285/
https://ncbi.nlm.nih.gov/pubmed/29515022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97493
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