An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm

Thoracic aortic aneurysm (TAA) has been associated with mutations affecting members of the TGF-β signaling pathway, or components and regulators of the vascular smooth muscle cell (VSMC) actomyosin cytoskeleton. Although both clinical groups present similar phenotypes, the existence of potential com...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lino Cardenas, Christian L., Kessinger, Chase W., Cheng, Yisha, MacDonald, Carolyn, MacGillivray, Thomas, Ghoshhajra, Brian, Huleihel, Luai, Nuri, Saifar, Yeri, Ashish S., Jaffer, Farouc A., Kaminski, Naftali, Ellinor, Patrick, Weintraub, Neal L., Malhotra, Rajeev, Isselbacher, Eric M., Lindsay, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843596/
https://ncbi.nlm.nih.gov/pubmed/29520069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03394-7
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