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Inhibition of the methyltranferase EZH2 improves aortic performance in experimental thoracic aortic aneurysm
Loss-of-function mutations in genes encoding contractile proteins have been observed in thoracic aortic aneurysms (TAA). To gain insight into the contribution of contractile protein deficiency in the pathogenesis of TAA, we examined human aneurysm samples. We found multiple contractile gene products...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5922285/ https://ncbi.nlm.nih.gov/pubmed/29515022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97493 |
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