Structural basis of ligand binding modes at the neuropeptide Y Y(1) receptor

Neuropeptide Y (NPY) receptors belong to the G protein-coupled receptor (GPCR) superfamily and play important roles in food intake, anxiety and cancer regulation(1,2). The NPY/Y receptor system has emerged as one of the most complex networks with three peptide ligands (NPY, peptide YY and pancreatic...

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Udgivet i:Nature
Main Authors: Yang, Zhenlin, Han, Shuo, Keller, Max, Kaiser, Anette, Bender, Brian J., Bosse, Mathias, Burkert, Kerstin, Kögler, Lisa M., Wifling, David, Bernhardt, Guenther, Plank, Nicole, Littmann, Timo, Schmidt, Peter, Yi, Cuiying, Li, Beibei, Ye, Sheng, Zhang, Rongguang, Xu, Bo, Larhammar, Dan, Stevens, Raymond C., Huster, Daniel, Meiler, Jens, Zhao, Qiang, Beck-Sickinger, Annette G., Buschauer, Armin, Wu, Beili
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920736/
https://ncbi.nlm.nih.gov/pubmed/29670288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0046-x
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