The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation

We report data on the structural dynamics of the neuropeptide Y (NPY) G-protein-coupled receptor (GPCR) type 1 (Y1R), a typical representative of class A peptide ligand GPCRs, using a combination of solid-state NMR and molecular dynamics (MD) simulation. First, the equilibrium dynamics of Y1R were s...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Vogel, Alexander, Bosse, Mathias, Gauglitz, Marcel, Wistuba, Sarah, Schmidt, Peter, Kaiser, Anette, Gurevich, Vsevolod V., Beck-Sickinger, Annette G., Hildebrand, Peter W., Huster, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7727705/
https://ncbi.nlm.nih.gov/pubmed/33255213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235489
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