Structural basis for ligand recognition of the neuropeptide Y Y(2) receptor

The human neuropeptide Y (NPY) Y(2) receptor (Y(2)R) plays essential roles in food intake, bone formation and mood regulation, and has been considered an important drug target for obesity and anxiety. However, development of drugs targeting Y(2)R remains challenging with no success in clinical appli...

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Vydáno v:Nat Commun
Hlavní autoři: Tang, Tingting, Hartig, Christin, Chen, Qiuru, Zhao, Wenli, Kaiser, Anette, Zhang, Xuefeng, Zhang, Hui, Qu, Honge, Yi, Cuiying, Ma, Limin, Han, Shuo, Zhao, Qiang, Beck-Sickinger, Annette G., Wu, Beili
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854658/
https://ncbi.nlm.nih.gov/pubmed/33531491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21030-9
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