Structural basis for ligand recognition of the neuropeptide Y Y(2) receptor

The human neuropeptide Y (NPY) Y(2) receptor (Y(2)R) plays essential roles in food intake, bone formation and mood regulation, and has been considered an important drug target for obesity and anxiety. However, development of drugs targeting Y(2)R remains challenging with no success in clinical appli...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Tang, Tingting, Hartig, Christin, Chen, Qiuru, Zhao, Wenli, Kaiser, Anette, Zhang, Xuefeng, Zhang, Hui, Qu, Honge, Yi, Cuiying, Ma, Limin, Han, Shuo, Zhao, Qiang, Beck-Sickinger, Annette G., Wu, Beili
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854658/
https://ncbi.nlm.nih.gov/pubmed/33531491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21030-9
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