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Neuropeptide Y receptors: how to get subtype selectivity

The neuropeptide Y (NPY) system is a multireceptor/multiligand system consisting of four receptors in humans (hY(1), hY(2), hY(4), hY(5)) and three agonists (NPY, PYY, PP) that activate these receptors with different potency. The relevance of this system in diseases like obesity or cancer, and the d...

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Autores principales: Pedragosa-Badia, Xavier, Stichel, Jan, Beck-Sickinger, Annette G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563083/
https://ncbi.nlm.nih.gov/pubmed/23382728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2013.00005
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