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Characterisation of Neuropeptide Y Receptor Subtypes by Synthetic NPY Analogues and by Anti-receptor Antibodies‡

Neuropeptide Y (NPY), a 36-mer neuromodulator, binds to the receptors Y(1), Y(2), Y(4) and Y(5) with nanomolar affinity. They all belong to the rhodopsin-like G-protein coupled, seven transmembrane helix spanning receptors. In this study, Ala-substituted and centrally truncated NPY analogues were co...

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Publicado en:Molecules
Main Authors: Eckard, Christophe P., Cabrele, Chiara, Wieland, Heike A., Beck-Sickinger, Annette G.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236447/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/60500448
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