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Blockade of neuropeptide Y(2) receptors and suppression of NPY's anti-epileptic actions in the rat hippocampal slice by BIIE0246

1. Neuropeptide Y (NPY) has been shown to suppress synaptic excitation in rat hippocampus by a presynaptic action. The Y(2) (Y(2)R) and the Y(5) (Y(5)R) receptors have both been implicated in this action. We used the non-peptide, Y(2)R-selective antagonist, BIIE0246, to test the hypothesis that the...

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Autori principali: Bahh, Bouchaïb El, Cao, Jeffrey Q, Beck-Sickinger, Annette G, Colmers, William F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573380/
https://ncbi.nlm.nih.gov/pubmed/12055128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704751
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